%0 Conference Paper %B International Workshop on Health Intelligence %D 2019 %T Explaining multi-label black-box classifiers for health applications %A Cecilia Panigutti %A Guidotti, Riccardo %A Monreale, Anna %A Pedreschi, Dino %K Explainable Machine Learning %K Healthcare %X Today the state-of-the-art performance in classification is achieved by the so-called “black boxes”, i.e. decision-making systems whose internal logic is obscure. Such models could revolutionize the health-care system, however their deployment in real-world diagnosis decision support systems is subject to several risks and limitations due to the lack of transparency. The typical classification problem in health-care requires a multi-label approach since the possible labels are not mutually exclusive, e.g. diagnoses. We propose MARLENA, a model-agnostic method which explains multi-label black box decisions. MARLENA explains an individual decision in three steps. First, it generates a synthetic neighborhood around the instance to be explained using a strategy suitable for multi-label decisions. It then learns a decision tree on such neighborhood and finally derives from it a decision rule that explains the black box decision. Our experiments show that MARLENA performs well in terms of mimicking the black box behavior while gaining at the same time a notable amount of interpretability through compact decision rules, i.e. rules with limited length. %B International Workshop on Health Intelligence %I Springer %G eng %U https://link.springer.com/chapter/10.1007/978-3-030-24409-5_9 %R 10.1007/978-3-030-24409-5_9